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New findings on Kiwifruit major allergen brings new hope to patients

Food allergies can induce life threatening symptoms. Therefore, precise diagnosis, identification of marker allergens as risk factors for severe reactions and understanding the molecular mechanisms of the immune system are key.

People who suffer from kiwifruit allergy are more likely to experience symptoms from mild unpleasant reactions in the oral cavity up to very severe life threatening anaphylaxis. Act d 1, the major kiwifruit allergen, usually induces rather severe symptoms. This is partly due to the fact that this protein resists digestion and can actively pass through the intestinal barrier.
For kiwifruit allergy, like many other food allergies, there is currently no active immunotherapy available. However, for some food allergies there is hope: the first data of allergen specific immunotherapy for food allergies will be presented at the International Symposium on Molecular Allergology, ISMA 2013, meeting in Vienna. Updates on clinical trials for pollen immunotherapies will also be summarised. Additionally, another highlight of the meeting will deal with bee and wasp venom allergy: By fine tuning allergen specific diagnosis - patient tailored immunotherapy either for bee or wasp venom or a combination of both, can be offered.